News Spotlight

Sunday, December 10, 2017

Making Antibiotic-Resistant Bacteria Treatable Again

Transport proteins called efflux pumps, and their role in creating drug-resistance in bacteria, could lead to improving effectiveness of drugs against life-threatening diseases and perhaps even bring defunct antibiotics back to prominence. Some life-threatening infections do not respond to antibiotics because efflux pumps inside a particular type of infectious microbe called Gram-negative bacteria flush out antibiotics before the drugs can work. One type of efflux pump, which until recently had only been studied in parts, was recently modeled in its entirety and simulated using supercomputers at Los Alamos National Laboratory.



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